Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Gwen must hit something to recast her Ultimate, try to evade her between casts.
Gwen needs to attack a few times to set up her damage, so try to get the jump on her.
Gwen's Hallowed Mist shroud will only follow her once, after that it will dissipate when she leaves.
The stats provided here underscore some valuable Cassiopeia against Gwen counter statistics that can help you grasp the differences and similarities between the two. For instance, Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is better than Gwen’s KDA ratio of NaN, showing that Cassiopeia may be more central to her team's team fighting capacity than Gwen..
Cassiopeia often has a similar longest killing spree as her foe does. Typically, she receives less damage than Gwen. This is usually reflective of different amounts of tankyness, but it can also imply that the one champion has less mobility and thus is unable to kite away from further harm when engaged or poked.
Both League champions are great champions. Both champs have their strengths, weaknesses, and counters. In League's current meta, Cassiopeia usually wins when taking on Gwen, with a 53.2% win rate. Thus, Cassiopeia makes a great counter to Gwen.
While Cassiopeia does have a higher win rate compared to Gwen, when on opposite teams, Cassiopeia also has a much greater learning curve that makes her a more time consuming champion to learn and master. You should be be fine when picking Cassiopeia into Gwenas her relative depth means that you may not be able to reach her full potential without a lot of practice beforehand.
Moreover, Cassiopeia also has a good amount of CC and other utility, a similar amount to Gwen. This makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there is not one best champion in League of Legends, in Cassiopeia vs Gwen matchups, Cassiopeia is the better champion with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your allied champions during late stage team fights.
Cassiopeia is a great counter for Gwen. Focus your actions on keeping up your CS and clearing objectives. If you do that, you should do very well as Cassiopeia against Gwen.
If you would like to truly master Cassiopeia to counter Gwen during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tips and tricks for this matchup. If you listen to the build and suggestions displayed above, you will increase your win rate significantly and be that much closer to League of Legends pro players.
Cassiopeia on average accumulates a similar amount of CS as Gwen. Champs who typically don't get many minion kills typically don't need much CS to be valuable teammates, such as sup champs. These kinds of champions are able to scale well off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, often require a lot of items to be effective. In either case, try to exceed the numbers reported here to do well.
The most important items to use in your Cassiopeia versus Gwen build consist of Liandry's Anguish, Rylai's Crystal Scepter, and Zhonya's Hourglass. When Cassiopeia included at least these three items in her build, she performed significantly better vs Gwen than with most other typical item sets. In fact, Cassiopeia had an average winrate of 53.2% when countering Gwen with this counter build.
To have the highest chance of vanquishing Gwen as Cassiopeia, you should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the rune builds players chose for Cassiopeia vs Gwen face-offs, this mix of runes yielded the best win rate. In fact, these runes provided a 53.2% win rate overall.
By default, tips, statistics, and builds on how to beat Gwen as Cassiopeia are displayed for all skill levels, merged. To filter the statistics and builds to a specific player tier, you can use the selection menu earlier in the counter matchup guide.