Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Karma's passive lowers her Mantra cooldown when she hits enemy champions with abilities and basic attacks. Deny her from getting free hits on you.
Karma's Soulflare erupts for bonus damage in the area in which it's placed. React quickly and escape the circle to avoid taking heavy damage.
Focused Resolve is a strong disengage tool. Create distance to avoid being rooted and seek to engage afterwards.
The stat comparisons provided here highlight some vital Cassiopeia versus Karma counter statistics that may help you understand the differences between the pair. For instance, Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karma’s ratio of NaN, indicating that Cassiopeia may be more central to her team's team fighting capacity than Karma. This observation is in large part fueled by the difference in kills.
Cassiopeia usually has a much larger longest killing spree than her foe does. On average, she takes more damage than Karma. This is usually reflective of differing health capacities; however, it can also illustrate that the one champ has less mobility and thus is not able to flee from further harm when engaged or poked.
Both League of Legends champs are great. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Cassiopeia usually wins when taking on Karma, with a 53.4% win rate. Thus, Cassiopeia makes a great counter for Karma.
While Cassiopeia does have a higher win rate than Karma, when they face off with one another, Cassiopeia also has a much greater level of difficulty that makes her a more challenging champ to pick up and master. You don't need to be too worried when picking Cassiopeia into Karmaas her relative depth means you may not be able to reach her full potential without a significant amount of practice beforehand.
Moreover, Cassiopeia also has a good amount of CC and other utility, a similar amount to Karma. This often makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there is not one best champion in League of Legends, in Cassiopeia vs Karma matchups, Cassiopeia is the better champion with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your allied champions during teamfights.
Cassiopeia is a great counter for Karma. Focus your tactics on increasing your gold income and clearing objectives. If you are able to do that, you should do very well as Cassiopeia against Karma.
To learn all of the intricacies of Cassiopeia in order to counter Karma during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tips and tricks for this matchup. If you pay attention to the build and stats shown above, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Cassiopeia most often racks up much more CS as Karma. Champs who on average don't earn much CS often don't require much CS to be effective, such as supports. They are able to scale properly off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, often require a lot of items to be effective. In either situation, try to surpass the values reported on this page to do well.
The most important items to focus on in your Cassiopeia versus Karma build include Everfrost, Seraph's Embrace, and Rylai's Crystal Scepter. When Cassiopeia combined at least these three pieces in her build, she performed significantly better countering Karma than with many other typical counter builds. In fact, Cassiopeia boasted an average win rate of 53.4% when countering Karma with this counter build.
To have the greatest probability of coming out on top against Karma as Cassiopeia, you should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the runes players used for Cassiopeia vs Karma matchups, this order of runes resulted in the best win rate. Notably, these runes gave a 53.4% winrate overall.
By default, tips, statistics, and builds on how to beat Karma as Cassiopeia are given for all ranked divisions. If you would like to scope the statistics and builds to a particular division, you may use the selection menu located earlier in the counter matchup guide.