League of Legends Karthus players could find him to be a challenging champ to build out properly. You'll see that his build is modified when he is playing against either diversified or specialized team comps, indicating you shouldn't select the same Karthus build every single round of League of Legends
The best items to include in your champ's build are: Tempête de Luden, Coiffe de Rabadon, and Flamme-ombre. Players who added these items in their setups had a much higher win rate than those who utilized other Karthus builds. Moreover, if you are fighting a well-mixed enemy team composition, you should really consider grabbing him the Domination, and Précision runes. In recent matches, he won the largest number of his matches when using these runes.
We calculated our Karthus build guidance by examining 15 381 recently ranked LoL games with him selected. We only advise the top winrate Karthus builds that were used by ranked gamers enough times for us to advise them. With so many rounds in our dataset, we are very confident in our recommended builds.