LoL Anivia players will find her to be a challenging character to build out properly. You'll see that her build varies when she is playing against either generic or highly focused team comps, indicating you should not take the same Anivia build every round of League of Legends
The most critical items to include in your champ's build are: Dolore di Liandry, Abbraccio serafico, and Copricapo di Rabadon. Those who added these items in their setups had a better winrate than players who used other Anivia builds. Likewise, if you are playing a mixed enemy team comp, you should strongly consider getting her the Dominazione, and Stregoneria runes. In recent matches, she won the largest percentage of her rounds when using these runes.
We set our Anivia build suggestions by analyzing 26.778 recently ranked League matches with her in them. We only recommend the best winrate Anivia builds that have been built by ranked LoL players enough times for us to advise them. With so many matches in our data, we are very confident in our recommended builds.