League of Legends Cassiopeia players may find her to be a complex champ to build out properly. You'll notice that her build varies when she is up against either well-rounded or specialized team comps, demonstrating you shouldn't take the same Cassiopeia build every game of League of Legends
The best items to incorporate into your champion's build are: Gelo perenne, Scettro di cristallo di Rylai, and Spirito cosmico. Players who added these pieces in their kits had a much better winrate than players who worked towards other item builds for Cassiopeia. Likewise, if you are trying to beat a varied enemy team arrangement, you should really consider grabbing yourself the Precisione, and Determinazione runes. In recent matches, she won the largest percentage of her matches when built with these runes.
We calculated our Cassiopeia build suggestions by examining 16.592 recently ranked League matches with her in them. We only recommend the best winrate Cassiopeia builds that have been used by ranked players enough times for us to advise them. With so many rounds in our dataset, we are quite confident in our provided builds.