League of Legends Karma players will likely find her to be a challenging character to build out properly. You will see that her build changes when she is up against either diversified or highly focused team compositions, indicating you shouldn't select the same Karma build every round of League of Legends
The most essential items to use in your champ's build are: Canto di guerra di Shurelya, Redenzione, and Incensiere ardente. Players who included these pieces in their kits had a better winrate than players who worked towards other builds for Karma. Moreover, if you are battling a mixed enemy team comp, you should strongly consider getting Karma the Stregoneria, and Determinazione runes. In recent matches, she won the largest fraction of her rounds when equipped with these runes.
We established our Karma build suggestions by analyzing 44.454 recently ranked LoL games with her in them. We only propose the highest winrate Karma builds that have been built by ranked gamers enough times for us to suggest them. With so many rounds in our data, we are confident in our provided builds.