The best champions not in lane to counter Karthus include Aphelios, Zeri, and Samira. These are all great at countering Karthus with high win rates over 61%. Even if these Karthus counter picks are not used in the same position as you, it's not a good idea to choose him into any of these matchups. They will usually destroy Karthus.
Yet, if the opposite team brings either Ziggs or Tahm Kench, Karthus mains should strongly consider picking him, as he easily dominates these champions with win rates over 53% against each ofthem.
To see the details and best Karthus counter builds for a specific matchup, you can click the related row in one of the tables above. If you want specific Ashe counters not highlighted above, you may use the filters below to find details on your specific Karthus matchup.
To limit the Karthus counters to a particular ranked tier only, pick the desired tier from the dropdown menu above. The recommended champion counters will be revised. If you would like great champion pairings for your own allies to advance your win percentage, take a look at our Karthus synergies.
We comb through millions of League of Legends matches pulled directly from Riot Games servers each week to give you an advantage. We analyze the data using advanced algorithms to bring you the most accurate Karthus counters online. Having evaluated so many matches gives us lots of faith in our conclusions.
The Karthus counter matchups shown below include data from Silver+ tiers and champions in all positions. Click an individual Karthus matchup to see a detailed build, stats, and advice to win your next fight. You will also have the opportunity to further refine your tier selection.