League of Legends Nocturne players will likely find him to be a difficult champion to build out properly. You'll find that his build is modified when he is fighting either diversified or highly focused team compositions, indicating you shouldn't follow the same Nocturne build every single game of League of Legends
The most important items to use in your champion's build are: Eclissi, Angelo custode, and Danza della Morte. Those who included these pieces in their setups had a much higher winrate than those who tried for other Nocturne builds. Likewise, if you are battling a well-mixed enemy team comp, you should strongly consider getting Nocturne the Precisione, and Dominazione runes. In recent games, he won the largest number of his rounds when equipped with these runes.
We set our Nocturne build suggestions by examining 82.320 recently ranked League of Legends rounds with him selected. We only advise the best winrate Nocturne builds that were used by ranked players enough times for us to advise them. With so many matches in our dataset, we are quite confident in our provided builds.