Because of Lissandra's K/D/A and utility, she has a fairly average overall win rate. She does very well in the early game, with a winrate of 50.1% in that phase. Unfortunately, she does very poorly in the late game, where Lissandra's win rate is 46.2%., The difference between her best and worst game phases is about 3.9%. This sizeable difference makes it clear that her power spikes and wanes in different phases of the round. Prepare accordingly.
Lissandra has been used somewhat often in recent ranked League of Legends matches. In the current meta, her popularity is 4.2%. Hardly anyone sees her as a threat. She has only been banned in roughly 2.3% of League rounds.
You can see her typically used in the middle position. However, that is not the best position for her. The highest win rate position for Lissandra is support (50,5%). At this time, Lissandra's meta game is focused on dealing damage. In particular, her kit should mostly be centered around magical damage. Furthermore, she is a pretty good tank champ. Dealing physical damage is the least critical part of Lissandra’s build.
If you are not comfortable with her skills and gameplay, you may find it difficult picking her up for the first time. Many players consider her to not be a tough champion to get good at. Lissandra primarily deals magic damage (90% of her total damage). She doesn't deal a lot of other damage types and should not be played as hybrid damage dealer..
Lissandra deals a decent amount of damage in a regular ranked game (19.440 damage). You may want to focus on developing her as a powerful champion to defeat your enemies.
She is an average damage dealer on the Rift with 5.4 kills on average each game. That is one of the highest kill rates among all middles. Furthermore, she has a relatively typical average champion death count (5.6 deaths). Additionally, Lissandra's KDA is usually high with an average KDA ratio of 2.4 as well as 8.2 assists per game.