LoL Kai'Sa players may find her to be a difficult champ to build out properly. You'll see that her build varies when she is playing against either generic or specialized team comps, showing you should not select the same Kai'Sa build every single round of League of Legends
The most critical items to incorporate into your champ's build include: Kraken Slayer, Guardian Angel, and Infinity Edge. Those who included these pieces in their setups had a greater winrate than players who tried for other item builds for Kai'Sa. Similarly, if you are playing a mixed enemy team comp, you should really consider grabbing Kai'Sa the Domination, and Sorcery runes. In recent games, she won the greatest fraction of her matches when built with these runes.
We came up with our Kai'Sa build suggestions by analyzing 177,997 recently ranked League games with her selected. We only propose the best winrate Kai'Sa builds that were used by ranked gamers enough times for us to advise them. With so many games in our dataset, we are quite confident in our recommended builds.