Timing Flash Frost with Frostbite can lead to devastating combinations.
It can be very difficult for enemy champions to kill her egg early in game. Seize the advantage by playing aggressively.
Anivia is extremely reliant on Mana for Glacial Storm. Try getting items with Mana or going for a Crest of the Ancient Golem buff on Summoner's Rift.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stat comparisons shown on this page show several influential Anivia against Karthus matchup statistics that may help you realize the differences and similarities between this pair of champions. For instance, Anivia’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karthus’s ratio of NaN, showing that Anivia may be more central to her team's team fighting capability than Karthus..
Anivia normally has a slightly smaller longest kill spree than her enemy does. Commonly, she receives a similar amount of damage to Karthus. This often reflects differing health capacities, yet it can also illustrate that the one champ has less mobility and thus is not able to flee from additional damage when engaged or poked.
Both LoL champs are great champions. Both have their strengths, weaknesses, and counters. In League's current meta, Anivia usually wins when taking on Karthus, with a 51.9% win rate. Thus, Anivia makes a good counter for Karthus.
While Anivia does have a higher win rate than Karthus, when on opposite teams, Anivia also has a much greater level of difficulty that makes her a more complex character to learn. You should be careful when picking Anivia into Karthusas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Furthermore, Anivia has some amount of CC and other utility, a similar amount to Karthus. This often makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there isn't one best champion in League of Legends, in Anivia vs Karthus matchups, Anivia is the better champ with a higher win rate, more champion depth, and a similar amount of utility to help out your allies during team fights.
Anivia is a decent counter to Karthus. You will do well by focussing your strategy on increasing your gold and cs and taking out objectives. If you do that, you should do very well as Anivia against Karthus.
To truly master Anivia to counter Karthus during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tips and tricks for this matchup. If you pay attention to the build and suggestions shown above, you will grow your win rate significantly and be closer to League of Legends pro players.
Anivia on average racks up more CS compared to Karthus. Champs who typically don't earn much CS usualy don't need much CS to be effective, such as supports. They are able to scale properly off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often have to have a lot of items to be effective. In either case, try to do better than the values shown here to do well.
The most important items to use in your Anivia versus Karthus build include Liandry's Anguish, Seraph's Embrace, and Zhonya's Hourglass. When Anivia combined at least these three pieces in her build, she did much better countering Karthus than with most other common builds. In fact, Anivia boasted an average winrate of 51.9% battling Karthus with this counter build.
To have the highest probability of annihilating Karthus as Anivia, Anivia players should take the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Presence of Mind, and Coup de Grace runes from the Domination and Precision rune sets. Of all the runes we have analyed for Anivia vs Karthus battles, this combination of runes yielded the greatest win rate. Moreover, these runes provided a 51.9% winrate overall.
By default, tips, statistics, and builds on how to beat Karthus as Anivia are shown for all skill levels combined. If you would like to filter the statistics and builds to a particular player tier, you can use the selection menu located earlier on the page.