Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Pop Blossom's warning visuals are invisible if Neeko is disguised.
Standing behind minions against Neeko is very dangerous as Tangle-Barbs become stronger.
The stats provided here clarify some important Cassiopeia versus Neeko matchup statistics that can help you realize the distinctions between this pair of champs. Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is better than Neeko’s ratio of NaN, showing that Cassiopeia may be more central to her team's team fighting capability than Neeko..
Cassiopeia typically has a similar longest killing spree as her foe does. On average, she takes more damage than Neeko. This often reflects differing health capacities, but it can also imply that the champion with higher health has less agility and thus is not able to flee from additional damage when poked or engaged.
Both League of Legends champs are great. Both have their pros and cons. In the game's current meta, Cassiopeia usually fairs equally well when facing off against Neeko, with a 49.6% win rate. Therefore, Cassiopeia makes an ok counter for Neeko.
While Cassiopeia does have a lower win rate than Neeko, when facing one another, Cassiopeia also has a much greater difficulty level that makes her a more complex character to learn. You still need to be cautious when picking Cassiopeia into Neekoas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Additionally, Cassiopeia also has a good amount of utility and CC, a similar amount to Neeko. This often makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there isn't a single best champion overall in League of Legends, in Cassiopeia vs Neeko matchups, Neeko is the better champion with a similar win rate, more champion depth, and a similar amount of utility to help out your allied champions during teamfights.
Cassiopeia is a somewhat poor counter to Neeko. Focus your play on maximizing your gold income and clearing objectives. If you are able to do that, you should do very well as Cassiopeia against Neeko.
If you would like to learn all of the intricacies of Cassiopeia in order to counter Neeko during both the laning and mid / late game phases of League of Legends, you should continue reading to pick up a few extra lessons on this matchup. If you listen to the build and suggestions displayed here, you should grow your win rate significantly and be closer to League of Legends pro players.
Cassiopeia most often accumulates a similar amount of CS compared to Neeko. Champs who typically don't acquire much CS often don't require much CS to be effective, such as sup champs. They are able to scale well off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, often need a lot of items to be effective. In either situation, try to do better than the numbers displayed here to do well.
The top items to prioritize in your Cassiopeia versus Neeko build include Liandry's Anguish, Rylai's Crystal Scepter, and Zhonya's Hourglass. When Cassiopeia bought at least these three items in her build, she did much better when fighting Neeko than with many other typical builds. In fact, Cassiopeia had an average winrate of 49.6% when countering Neeko with these items in her kit.
To have the best likelihood of vanquishing Neeko as Cassiopeia, you should equip the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the rune builds players chose for Cassiopeia vs Neeko matchups, this mixture of runes yielded the best win rate. In fact, these runes gave a 49.6% win rate overall.
If you want to see Cassiopeia vs Neeko tips and matchup stats and build suggestions for a a distinct player tier, please choose one from the selection menu above. At first, the statistics and guides shown are calculated using every game finished with both champs.