Cassiopeia Build
The Best Runes, Items, and Advice to Dominate Your Competition

Cassiopeia
187,770 LoL Matches Analyzed
Summary
Our Cassiopeia builds come from our analysis of 187,770 recently ranked Cassiopeia rounds. Only the top winrate Cassiopeia builds that are also in common use are advised. Since we have so many matches in our database, we are quite sure that we can produce high quality builds to help ensure you win your next game!
If you would like more focused build tips and tactics, feel free to read our tips at the bottom of the page. Additionally, Cassiopeia builds dedicated to a unique skill rank can be displayed by choosing a different division from the dropdown menu located above. The recommended Cassiopeia build will be specific to that division’s meta.
Best Cassiopeia Runes
If you are playing a well-mixed enemy team composition, you should really consider grabbing her the Electrocute, Taste of Blood, Eyeball Collection, Ravenous Hunter, Manaflow Band, and Transcendence runes. In recent games, she won the greatest percentage of her matches when equiped with these runes. Yet, if you are trying to beat a more homogenous enemy team comp, such as an AD centric or a crowd control heavy team, you should instead look below to view the best Cassiopeia runes to defeat your particular enemy team.
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Best Items for Your Cassiopeia Build
The most important items to use in your Cassiopeia build are: Liandry's Anguish, Rylai's Crystal Scepter, Zhonya's Hourglass, and Cosmic Drive. Yet, like our rune suggestions, you can also get quality, focused, Cassiopeia item builds farther down for the specific enemy team composition you are playing in your ongoing game. Players who included these pieces in their builds had a greater winrate than those who tried for other builds for Cassiopeia.
Guide to Playing with Cassiopeia
- Cassiopeia is great at harassing and zoning enemies so make sure your enemy laner cannot last hit minions.
- Maximize damage from Twin Fang by using it on stationary neutral monsters or stunned targets.