Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Ryze is especially dangerous to opponents that are marked with Flux.
Crowd controlling Ryze during Realm Warp's windup will cancel the portal.
Use Realm Warp's windup time to figure out how to deal with what may be coming out of the portal.
The stats shown on this page emphasize some important Cassiopeia versus Ryze counter statistics that can help us explain the differences between the two. For instance, Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is more than Ryze’s KDA ratio of NaN, demonstrating that Cassiopeia may be more central to her team's team fighting effectiveness than Ryze..
Cassiopeia often has a slightly larger longest kill spree than her matchup does. Commonly, she takes a similar amount of damage to Ryze. This is usually reflective of differing health capacities, but it can also show that the one champ has less agility and thus is unable to flee from additional harm when poked or engaged.
Both LoL champions are great. Both have their strengths, weaknesses, and counters. In League's current meta, Cassiopeia usually wins when facing off against Ryze, with a 57.0% win rate. As a result, Cassiopeia makes a fantastic counter to Ryze.
While Cassiopeia does have a much higher win rate than Ryze, when on opposite teams, Cassiopeia also has a much greater level of difficulty that makes her a more challenging champ to learn. You don't need to be too worried when picking Cassiopeia into Ryzeas her relative depth means you may not be able to reach her full potential without a lot of practice beforehand.
Additionally, Cassiopeia has a good amount of utility and CC, a similar amount to Ryze. This often makes her just as valuable during teamfights, especially when trying to counter champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Cassiopeia vs Ryze matchups, Cassiopeia is the better champion with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your team members during team fights.
Cassiopeia is a great counter to Ryze. Focus your tactics on maximizing your gold income and taking out objectives. If you are able to do that, you should hold your own as Cassiopeia against Ryze.
If you would like to learn all of the intricacies of Cassiopeia to counter Ryze during both the laning and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this matchup. If you pay attention to the build and stats displayed above, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Cassiopeia often picks up a similar amount of CS relative to Ryze. Champs who typically don't get much CS often don't need much CS to be effective, such as support champions. These kinds of champions are able to scale properly off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, often have to have several high cost items to be effective. In either situation, try to do better than the values reported on this page to do well.
The ideal items to use in your Cassiopeia versus Ryze build include Liandry's Anguish, Seraph's Embrace, and Rylai's Crystal Scepter. When Cassiopeia incorporated at least these three pieces in her build, she did significantly better vs Ryze than with most other commonly used builds. In fact, Cassiopeia had an average winrate of 57.0% when playing against Ryze with this counter build.
To have the greatest chance of annihilating Ryze as Cassiopeia, you should equip the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the runes players used for Cassiopeia vs Ryze battles, this blending of runes yielded the highest win rate. In fact, these runes provided a 57.0% winrate overall.
If you would like to get Cassiopeia vs Ryze tips and counter builds for a a particular player tier, feel free to choose one from the selection menu displayed above. By default, the stats and guides displayed are computed using every match finished with these champs.