Use Arcane Shift to help line up your other skill shots.
You can line up Trueshot Barrage to hit multiple minion waves or even Monsters.
You can play Ezreal either as a Attack Damage carry or Ability Power carry depending on how you build him.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stat comparisons shown here highlight some important Ezreal versus Karthus counter statistics that may help you explain the distinctions between the two. As an example, Ezreal’s KDA ratio ([kills + assists] / deaths) of NaN is more than Karthus’s KDA ratio of NaN, demonstrating that Ezreal may be more central to his team's team fighting potential than Karthus..
Ezreal usually has a similar longest killing spree as his counter does. Commonly, he takes less damage than Karthus. This is usually reflective of differing health capacities, but it can also imply that the champ with higher HP has less agility and thus is unable to kite away from additional harm when poked or engaged.
Both League champs are great. Both have their pros and cons. In League's current meta, Ezreal usually fairs equally well when facing off against Karthus, with a 49.5% win rate. Thus, Ezreal makes an ok counter to Karthus.
While Ezreal does have a lower winrate than Karthus, when on opposite teams, Ezreal also has a greater learning curve that makes him a more difficult champ to develop with. You still need to be cautious when picking Ezreal into Karthusas his relative depth means you may not be able to unleash his full potential without a significant amount of practice beforehand.
Moreover, Ezreal also has almost no amount of utility and CC, a similar amount to Karthus. This often makes her just as valuable during team fights, especially when trying to counter champions with a ton of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Ezreal vs Karthus matchups, Karthus is the better champion with a similar win rate, similar champion depth, and a similar amount of utility to help out your teammates during late stage team fights.
Ezreal is a somewhat poor counter for Karthus. Focus your actions on keeping up your gold and cs and destroying objectives. If you do that, you should be able to stand on your own as Ezreal against Karthus.
If you would like to learn all of the intricacies of Ezreal in order to counter Karthus during both the laning and mid / late game phases of League of Legends, you should continue reading to gather a few extra tips and tricks for this matchup. If you pay attention to the build and suggestions shown above, you should grow your win rate significantly and be closer to League of Legends pro players.
Ezreal typically racks up more CS relative to Karthus. Champions who on average don't earn much CS typically don't require much CS to be valuable teammates, such as supports. These kinds of champions are capable of scaling well off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often require many items to be effective. In either situation, try to do better than the numbers reported here to do well.
The ideal items to focus on in your Ezreal versus Karthus build consist of Muramana, Trinity Force, and Voltaic Cyclosword. When Ezreal used at least these three pieces in his build, he did significantly better vs Karthus than with most other typical item sets. In fact, Ezreal had an average win rate of 49.5% when playing against Karthus with these items in his kit.
To have the greatest chance of vanquishing Karthus as Ezreal, you should equip the Press the Attack, Presence of Mind, Legend: Bloodline, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Of all the rune builds we have analyed for Ezreal vs Karthus LoL games, this combo of runes resulted in the highest win rate. In fact, these runes averaged a 49.5% win rate overall.
If you would like to get Ezreal versus Karthus tips and builds for a a distinct division rank, please choose one from the selection menu provided above. At first, the statistics and build suggestions displayed are computed using every match completed with both champions.