Kha'Zix vs Karthus Counter Build

How to Beat Karthus as Kha'Zix


We summarize our matchup stats from the millions of recently ranked League of Legends matches that we evaluate each week. This Kha'Zix against Karthus matchup guide resulted from an examination of 7,184 ranked rounds where both champs fought each other.

This particular matchup is fairly rare. Kha'Zix encounters Karthus in only 0.8% of his rounds. Kha'Zix does a good job of countering Karthus. On average, Kha'Zix wins a whopping 52.0% of the time the champions face one another in. In Kha'Zix versus Karthus matches, Kha'Zix’s team is 5.0% more likely to earn first blood. This implies that he probably will get first blood against Karthus.

Matchups Analyzed


Win Rate


Team First Blood


Best Kha'Zix Items to Counter Karthus

The best items to use in your Kha'Zix versus Karthus build consist of Youmuu's Ghostblade, Edge of Night, and The Collector. When Kha'Zix combined at least these three items in his build, he performed much better against Karthus than with most other commonly used item sets.

Youmuu's Ghostblade Item Edge of Night Item The Collector Item

Best Kha'Zix Runes to Counter Karthus

To have the best probability of vanquishing Karthus as Kha'Zix, you should equip the Conqueror, Triumph, Legend: Tenacity, Coup de Grace, Sudden Impact, and Ravenous Hunter runes. Out of all the runes players used for Kha'Zix vs Karthus matchups, this combination of runes yielded the highest win rate. We have also included the top Karthus runes to counterpick against Kha'Zix to help you understand how he will probably be setup to try to beat your champ.

Best Kha'Zix Runes

Conqueror Rune Conqueror
Triumph Rune Triumph
Legend: Tenacity Rune Legend: Tenacity
Coup de Grace Rune Coup de Grace
Sudden Impact Rune Sudden Impact
Ravenous Hunter Rune Ravenous Hunter

Best Karthus Runes

Dark Harvest Rune Dark Harvest
Cheap Shot Rune Cheap Shot
Eyeball Collection Rune Eyeball Collection
Ultimate Hunter Rune Ultimate Hunter
Presence of Mind Rune Presence of Mind
Last Stand Rune Last Stand


The subsequent tables show some significant Kha'Zix vs. Karthus counter stats that can help us understand the differences and similarities between the two. Kha'Zix’s KDA ratio ([kills + assists] / deaths) of 2.4 is nearly equal to Karthus’s ratio of 2.1, demonstrating that Kha'Zix may be just as central to his team's team fighting effectiveness than Karthus.

Battle Stats


Kha'Zix Stats
9.5 7.2
Karthus Stats


Kha'Zix Stats
6.3 7.5
Karthus Stats


Kha'Zix Stats
5.7 8.8
Karthus Stats

Largest Killing Spree

Kha'Zix Stats
4.2 2.7
Karthus Stats

Damage Dealt

Kha'Zix Stats
18356 25817
Karthus Stats

Damage Taken

Kha'Zix Stats
32574 24407
Karthus Stats

Objective Stats

Towers Destroyed

Kha'Zix Stats
5.4 5
Karthus Stats

Inhibitors Destroyed

Kha'Zix Stats
0.9 0.9
Karthus Stats

Dragons Killed

Kha'Zix Stats
2.3 1.8
Karthus Stats

Barons Killed

Kha'Zix Stats
0.4 0.4
Karthus Stats

Gold Earned

Kha'Zix Stats
11802 11567
Karthus Stats

Minions Killed

Kha'Zix Stats
29 88
Karthus Stats

Kha'zix often has a much larger longest kill spree than his opponent does. Commonly, Kha'Zix takes more damage than Karthus. This often reflects different amounts of tankyness; however, it can also imply that the champion with higher health has less mobility and thus is unable to kite away from further damage when poked or engaged.

Kha'Zix usually takes many fewer minion kills than Karthus. Champs who on average don't acquire much CS normally don't require much CS to be useful. They are able to scale easily off their skills and stats alone. Yet, champions with scores of minion kills, such as ADCs, usually have to have a lot of items to be effective. In either situation, work to exceed the values presented here to do well.

By default, Kha'Zix vs Karthus tips, statistics, and build guide are shown for all ranked divisions combined. To scope the stats and builds to an individual division, you may use the selection menu menu located earlier on the page.

How We Analyze Our Matchups

For this counter guide, we analyzed 7184 Kha'Zix vs Karthus matchups from recent LoL games. We use rigorous data cleaning and processing methods to ensure that our counter stats are of the highest quality. You can rest assured that the recommended build to counter Karthus as Kha'Zix comes from real data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view the most relevant stats and items to your rank.