Ryze is especially dangerous to opponents that are marked with Flux.
Crowd controlling Ryze during Realm Warp's windup will cancel the portal.
Use Realm Warp's windup time to figure out how to deal with what may be coming out of the portal.
The stat comparisons provided here feature some important Senna vs. Ryze counter stats that can help us realize the distinctions between this pair of champs. As an example, Senna’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Ryze’s KDA ratio of NaN, showing that Senna may be more central to her team's team fighting capability than Ryze. This observation is largely caused by the differences in assists.
Senna usually has a similar longest killing spree as her counter does. Typically, she takes less damage than Ryze. This often reflects differing health capacities, but it can also show that the champ with increased HP has less agility and thus is unable to escape additional damage when engaged or poked.
Both League champions are great. Both champs have their pros and cons. In the game's current meta, Senna usually wins when trying to fight Ryze, with a 52.0% win rate. As a result, Senna makes a good counter to Ryze.
While Senna does have a higher win rate than Ryze, when they face off with one another, Senna also has a greater level of difficulty that makes her a more complex champ to learn and master. You still need to be cautious when picking Senna into Ryzeas her relative depth means you may not be able to unleash her full potential without a significant amount of practice beforehand.
Furthermore, Senna also has a good amount of CC and other utility, a similar amount to Ryze. This often makes her just as valuable during teamfights, especially when fighting champions with a ton of burst damage.
While there is not one best champion for every situation in League of Legends, in Senna vs Ryze matchups, Senna is the better champion with a higher win rate, similar champion depth, and a similar amount of utility to help out your team members during late stage team fights.
Senna is a decent counter to Ryze. You will do well by focussing your gameplay on keeping up your CS and clearing objectives. If you do that, you should do very well as Senna against Ryze.
If you would like to truly master Senna to counter Ryze during both the early game and mid / late game phases of League of Legends, you should continue reading to learn a few extra tricks and insights into this matchup. If you mind the build and suggestions displayed here, you will increase your win rate significantly and be that much closer to League of Legends pro players.
Senna often accumulates a lot less CS compared to Ryze. Champs who on average don't earn many minion kills typically don't require much CS to be effective, such as support champions. They are able to scale properly off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically have to have a lot of items to be effective. In either situation, try to do better than the numbers reported here to do well.
The top items to prioritize in your Senna versus Ryze build include Eclipse, Rapid Firecannon, and Umbral Glaive. When Senna combined at least these three pieces in her build, she performed much better versus Ryze than with most other commonly used counter builds. In fact, Senna had an average winrate of 52.0% when countering Ryze with this build.
To have the best likelihood of coming out on top against Ryze as Senna, you should equip the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Biscuit Delivery, and Approach Velocity runes from the Precision and Inspiration rune sets. Out of all the rune sets players picked for Senna vs Ryze fights, this order of runes yielded the best win rate. Notably, these runes averaged a 52.0% win rate overall.
By default, tips, stats, and builds on how to beat Ryze as Senna are displayed for all ranked divisions. If you would like to narrow the stats and builds to an individual skill level, you may use the selection menu above.