You can send the Maiden down a lane alone, be careful though, as she represents a large portion of your combat power.
You do not need to cast Awakening to regain the ability to cast Last Rites.
The Maiden will attempt to assist you in a fight, so choose your targets well.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
The stat comparisons provided here highlight several important Yorick against Karthus matchup statistics that may help you appreciate the distinctions between the pair. As an example, Yorick’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karthus’s KDA ratio of NaN, highlighting that Yorick may be more central to his team's team fighting capability than Karthus..
Yorick often has a slightly smaller longest kill spree than his opponent does. Typically, he takes more damage than Karthus. This commonly reflects different amounts of tankyness, but it can also show that the champion with more HP has less agility and thus is unable to escape further damage when poked or engaged.
Both LoL champions are great. Both have their pros and cons. In the game's current meta, Yorick usually wins when taking on Karthus, with a 53.8% win rate. Thus, Yorick makes a great counter to Karthus.
While Yorick does have a higher winrate compared to Karthus, when on opposite teams, Yorick also has a lower level of difficulty that makes him a less complex champion to pick up and master. You should be be fine when picking Yorick into Karthus.
Additionally, Yorick also has only a small amount of utility and CC, a similar amount to Karthus. This often makes her just as valuable during teamfights, especially when trying to counter champions with a lot of burst damage.
While there isn't a single best champion overall in League of Legends, in Yorick vs Karthus matchups, Yorick is the better champ with a noticably higher win rate, less champion complexity, and a similar amount of utility to help out your team members during late stage team fights.
Yorick is a great counter for Karthus. You will do well by focussing your play on increasing your gold income and taking out objectives. If you can do that, you should be able to stand on your own as Yorick against Karthus.
To truly master Yorick in order to counter Karthus during both the laning and mid / late game phases of League of Legends, you should keep reading to learn a few extra lessons on this matchup. If you pay attention to the build and stats presented here, you will increase your win rate significantly and be that much closer to League of Legends pro players.
Yorick on average gets more CS as Karthus. Champions who typically don't get much CS typically don't require much CS to be valuable teammates, such as sup champs. They are capable of scaling well off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, usually require a lot of items to be effective. In either case, try to do better than the numbers shown on this page to do well.
The most crucial items to focus on in your Yorick versus Karthus build include Divine Sunderer, Hullbreaker, and Serylda's Grudge. When Yorick included at least these three pieces in his build, he did a lot better vs Karthus than with many other commonly used builds. In fact, Yorick had an average winrate of 53.8% when playing against Karthus with these items in his kit.
To have the greatest probability of crushing Karthus as Yorick, you should equip the Conqueror, Triumph, Legend: Bloodline, Last Stand, Demolish, and Bone Plating runes from the Precision and Resolve rune sets. Out of all the runes players chose for Yorick vs Karthus battles, this combo of runes resulted in the greatest win rate. Notably, these runes provided a 53.8% winrate overall.
If you would like to see Yorick vs Karthus tips and builds for a a specific division rank, please select one from the selection menu provided above. At first, the statistics and strategies displayed are calculated using all rounds run with both champs.