Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The stats shown here clarify some influential Cassiopeia against Vex matchup stats that may help us appreciate the distinctions between the two. As an example, Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Vex’s ratio of NaN, showing that Cassiopeia may be more central to her team's team fighting potential than Vex..
Cassiopeia often has a similar longest killing spree as her matchup does. On average, she takes more damage than Vex. This typically indicates different amounts of tankyness; however, it can also imply that the one champ has less mobility and thus is not able to escape further damage when poked or engaged.
Both League of Legends champs are great. Both champs have their pros and cons. In the game's current meta, Cassiopeia usually wins when trying to fight Vex, with a 52.2% win rate. Thus, Cassiopeia makes a good counter for Vex.
While Cassiopeia does have a higher win rate than Vex, when they face off with one another, Cassiopeia also has a much greater difficulty level that makes her a more complex champion to learn. You don't need to be too worried when picking Cassiopeia into Vexas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Furthermore, Cassiopeia has a good amount of CC and other utility, a similar amount to Vex. This makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there isn't one best champion for every situation in League of Legends, in Cassiopeia vs Vex matchups, Cassiopeia is the better champ with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your team members during teamfights.
Cassiopeia is an above average counter to Vex. Make sure you focus your strategy on keeping up your CS and clearing objectives. If you do that, you should hold your own as Cassiopeia against Vex.
If you would like to truly master Cassiopeia to counter Vex during both the lane and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tips and tricks for this matchup. If you mind the build and suggestions shown here, you should increase your win rate significantly and be that much closer to League of Legends pro players.
Cassiopeia often racks up a similar amount of CS compared to Vex. Champs who on average don't earn much CS often don't have to have much CS to be valuable teammates, such as support champions. These kinds of champions are capable of scaling properly off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, usually have to have several high cost items to be effective. In either case, try to surpass the values displayed on this page to do well.
The best items to focus on in your Cassiopeia versus Vex build include Liandry's Anguish, Seraph's Embrace, and Rylai's Crystal Scepter. When Cassiopeia incorporated at least these three items in her build, she performed significantly better when fighting Vex than with many other common counter builds. In fact, Cassiopeia had an average winrate of 52.2% battling Vex with these items in her kit.
To have the highest chance of vanquishing Vex as Cassiopeia, Cassiopeia players should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the runes players chose for Cassiopeia vs Vex counter picks, this order of runes yielded the greatest win rate. Notably, these runes gave a 52.2% win rate overall.
By default, tips, statistics, and builds on how to beat Vex as Cassiopeia are displayed for all skill levels, merged. To scope the stats and builds to a specific player tier, you should use the selection menu located earlier on the page.