Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Rupture has a smoke cloud indicating the area it will strike. Try to watch out for it to prevent Cho'Gath from being able to combo his abilities.
Purchasing a few HP items decreases the chances of Cho'Gath killing you quickly.
Focus on preventing Cho'Gath from reaching his max size.
The stats provided here clarify several critical Karthus against Cho'Gath matchup statistics that can help you explain the distinctions between the pair. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Cho'Gath’s KDA ratio of NaN, showing that Karthus may be more central to his team's team fighting effectiveness than Cho'Gath..
Karthus usually has a slightly larger longest killing spree than his foe does. Commonly, he takes less damage than Cho'Gath. This often reflects differing health capacities, but it can also illustrate that the one champion has less mobility and thus is unable to escape further harm when poked or engaged.
Both League of Legends champions are great champions. Both have their pros and cons. In the game's current meta, Karthus usually wins when facing off against Cho'Gath, with a 52.3% win rate. Thus, Karthus makes a good counter to Cho'Gath.
While Karthus does have a higher win rate than Cho'Gath, when on opposite teams, Karthus also has a greater difficulty level that makes him a more difficult character to learn and master. You don't need to be too worried when picking Karthus into Cho'Gathas his relative depth means that you may not be able to unleash his full potential without a lot of practice beforehand.
Moreover, Karthus has some amount of utility and CC, a similar amount to Cho'Gath. This often makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there is not a single best champion in League of Legends, in Karthus vs Cho'Gath matchups, Karthus is the better champ with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your team members during teamfights.
Karthus is an above average counter for Cho'Gath. Make sure you focus your play on maximizing your CS and destroying objectives. If you can do that, you should do very well as Karthus against Cho'Gath.
To truly master Karthus to counter Cho'Gath during both the laning and mid / late game phases of League of Legends, you should continue reading to gather a few extra tricks and insights into this matchup. If you mind the build and stats shown above, you will grow your win rate significantly and be closer to League of Legends pro players.
Karthus usually racks up a similar amount of CS relative to Cho'Gath. Champs who typically don't earn many minion kills often don't need much CS to be valuable teammates, such as support champions. These kinds of champions are capable of scaling properly off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually require many items to be effective. In either case, try to exceed the numbers reported here to do well.
The top items to focus on in your Karthus versus Cho'Gath build consist of Liandry's Anguish, Void Staff, and Shadowflame. When Karthus included at least these three pieces in his build, he performed significantly better vs. Cho'Gath than with many other commonly used item sets. In fact, Karthus had an average win rate of 52.3% when playing against Cho'Gath with these items in his kit.
To have the highest probability of annihilating Cho'Gath as Karthus, Karthus players should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Of all the rune builds we have analyed for Karthus vs Cho'Gath fights, this composite of runes yielded the highest win rate. Notably, these runes provided a 52.3% win rate overall.
If you would like to view Karthus vs Cho'Gath tips and counter stats for a a particular division rank, please select one from the selection menu shown above. If viewing for the first time, the stats and build suggestions given are computed using every match with data with these champions.