Karthus vs Lissandra Counter Build

How to Win Karthus vs Lissandra Counter Matchup vs How to Beat Lissandra as Karthus in LoL

How to Beat Lissandra as Karthus

1,367 Karthus vs Lissandra Matchups Analyzed

Win Rate


First Blood


Best Karthus Items to Counter Lissandra

The ideal items to use in your Karthus versus Lissandra build include Zhonya's Hourglass, Demonic Embrace, and Liandry's Anguish. When Karthus bought at least these three pieces in his build, he did significantly better vs. Lissandra than with most other commonly used item sets.


8.3 | Karthus Lissandra | 6


7.5 | Karthus Lissandra | 6.9


10 | Karthus Lissandra | 9

Best Karthus Runes to Counter Lissandra

Dark Harvest Rune Dark Harvest
Cheap Shot Rune Cheap Shot
Eyeball Collection Rune Eyeball Collection
Ravenous Hunter Rune Ravenous Hunter
Presence of Mind Rune Presence of Mind
Last Stand Rune Last Stand
To have the best chance of crushing Lissandra as Karthus, Karthus players should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ravenous Hunter, Presence of Mind, and Last Stand runes. Out of all the rune sets that we analyzed for Karthus vs Lissandra battles, this sequence of runes resulted in the highest win rate. We have also included the top Lissandra runes to fend off Karthus to help you understand how she will likely be played to try to beat your champ.

Runes Lissandra Will Likely Use to Counter Karthus

Electrocute Rune Electrocute
Taste of Blood Rune Taste of Blood
Eyeball Collection Rune Eyeball Collection
Ultimate Hunter Rune Ultimate Hunter
Biscuit Delivery Rune Biscuit Delivery
Time Warp Tonic Rune Time Warp Tonic

Karthus vs Lissandra Counter Stats Summary

The stats shown on this page show some significant Karthus against Lissandra matchup statistics that may help us realize the distinctions between the two. Karthus’s KDA ratio ([kills + assists] / deaths) of 2.4 is close to Lissandra’s ratio of 2.2, indicating that Karthus may be just as central to his team's team fighting capability than Lissandra.

Karthus normally has a slightly larger longest killing spree than his opponent does. Commonly, Karthus receives more damage than Lissandra. This often reflects differing health capacities; however, it can also indicate that the one champ has less mobility and thus is unable to flee from additional damage when poked or engaged.

Karthus usually takes many fewer minion kills than Lissandra. Champs that do not get much CS normally don't require much CS to be useful. Instead, they are able to scale adequately off of their abilities alone. However, champs with a lot of CS, such as ADCs, usually have to have a lot of items to be useful. In either situation, work to do better than the averages shown here to do well.

If you need to see Karthus vs Lissandra tips and counter stats for a a specific division, please select one from the selection menu shown above. By default, the stats and strategies shown are calculated using every round completed with these champions.

Killing Spree

3 | Karthus Lissandra | 2.5

Damage Dealt

29,924 | Karthus Lissandra | 18,969

Damage Taken

24,515 | Karthus Lissandra | 21,308

Gold Earned

12,538 | Karthus Lissandra | 11,017

Minions Killed

77 | Karthus Lissandra | 153


5.5 | Karthus Lissandra | 5.5

Dragons Killed

2 | Karthus Lissandra | 2.1

Barons Killed

0.5 | Karthus Lissandra | 0.5


0.9 | Karthus Lissandra | 1

Karthus vs Lissandra Matchup Summary

We calculate our counter stats from the millions of recently rated League of Legends rounds that we evaluate every week. This Karthus against Lissandra counter review resulted from an examination of 1,367 ranked rounds where both champs fought one another.

This particular champ matchup is relatively uncommon. Karthus has to counter Lissandra in only 4.2% of his games. Karthus does a decent job of countering Lissandra. Typically, he wins a acceptable 51.0% of games the champs face each other in. In Karthus against Lissandra rounds, Karthus’s side is 4.0% less probable to obtain first blood, indicating that he probably won't be able to get first blood against Lissandra.

How We Analyze Our Champion Counters

For this counter guide, we analyzed 1,367 Karthus vs Lissandra matchups from recent LoL games. We use rigorous data cleaning and processing methods to ensure that our counter stats are of the highest quality. You can rest assured that the recommended build to counter Lissandra as Karthus comes from real data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view the most relevant stats and items to your rank.