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How to Synergize Karthus with Lissandra on the Same TeamKarthus is in the b tier of champions

Karthus with Lissandra

How to Win With Karthus and Lissandra Paired TogetherKarthus is in the a tier of champions
Mage
Mage

How to Synergize Karthus and Lissandra

based on 408 Karthus with Lissandra pairs
Win Rate
42.6 %
K/D/A
2.11
Pick Rate
0.8 %

How We Analyze Champion Pairings in LoL

Our servers download the results of from millions of League of Legends games directly from Riot Games each week. Karthus has gone into battle with Lissandra in 408 recently played, ranked games. By amassing so much complete data straight from the hosts of LoL, we are completely sure that we can showcase robust, accurate builds to help Karthus play with Lissandra. It is very rare for Karthus to play alongside Lissandra as teammates. This pairing has only occurred in approx. 0.8% of matches with Karthus.

Karthus Lissandra Synergy Summary

Unfortunately, Karthus does a terrible job of synergizing with Lissandra. On average, he wins a dismal 42.6% of the time the champions fight alongside one another. If you want to play better as Karthus when playing alongside Lissandra by figuring out how to better synergize your strategy with her, then look into the full build (with items, runes, summoner spells, and skills) below!

Best Karthus vs Lissandra Counter Build

Items

Starter Items

Time Target
Scorchclaw PupHealth Potion

Early Items

~5 Mins
Sapphire CrystalAmplifying Tome

Core Karthus Items

~22 Mins
Rabadon's DeathcapMalignanceLiandry's Torment

Optional Items

StormsurgeShadowflame

Summoner Spells

summonerexhaust summoner spell D
summonersmite summoner spell F

Skill Order

First skill for Karthus to level upq
>
Second ability for Karthus to level upe
>
Last skill for Karthus to max outw

Runes

DominationDark HarvestCheap ShotEyeball CollectionUltimate Hunter
SorceryTranscendenceGathering Storm
Adaptive ForceAdaptive ForceArmor
Karthus's passive ability p
Karthus's q ability q
Karthus's w ability w
Karthus's e ability e
Karthus's ultimate ability r
1
Q
2
E
3
Q
4
W
5
Q
6
R
7
Q
8
E
9
Q
10
E
11
R
12
E
13
E
14
W
15
W
16
R

Guide to Synergizing Karthus and Lissandra

Tips for Playing as Karthus with Lissandra

Lay Waste is very strong at farming minions and harassing enemy champions.

Ask your allies to help point out when you should use Requiem to get kills in different lanes.

Advice to Understand How Lissandra Will Play

Lissandra's abilities are shorter range than those of many mages. As a result, buying items that offer both ability power and defense, like Zhonya's Hourglass and Banshee's Veil, can be a great choice to help her both survive and deal damage.

Casting Glacial Path and then running in the opposite direction will leave your enemies uncertain which way you will actually go.

You can instantly use your ultimate on yourself by pressing the self cast key and the ultimate key at once (alt+R by default).

Karthus Lissandra Synergy Stats

Karthus Image
Win Rate
42.6 %
VS
Win Rate
57.4 %
Lissandra Image
7.4
< Kills >
7
8.1
< Deaths >
7.6
9.7
< Assists >
9.5
1.72
< Killing Sprees >
1.63
80
< Minions Killed >
88
0.86
< Dragons Killed >
0.89
0.25
< Inhibitors >
0.28
256
< Physical Damage >
246
29,111
< Magic Damage >
29,153
2,067
< True Damage >
2,031
31,435
< Damage Dealt >
31,430
30,773
< Damage Taken >
29,785
12,963
< Gold Earned >
12,799
1
< Towers >
1.08
0.21
< Baron Takedowns >
0.23
9,726
< Total Healing >
9,279
14,880
< Experience >
14,921
19
< Vision Score >
19
7
< Wards Placed >
7
221
< Time Dealing CC >
221

How to Play with Lissandra as Karthus in LoL

The Karthus Lissandra synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Lissandra, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.

Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Lissandra. His KDA worsened from NaN to NaN. This fall shows that Lissandra helps Karthus perform not as well in competitive League games. Yet, the small difference demonstrates that this performance change is not very impactful.

When Karthus tries to synergize with Lissandra, he gets a marginal improvement in his complete damage output. This change may signal that Lissandra provides protection for him to dish out more damage or that her allyship also helps extend the match's duration. Similarly, when Karthus is played with Lissandra on the same team, he usually scores many fewer killing sprees than when he plays without Lissandra. This is contrasting evidence that he is worse when playing synergisticly with Lissandra.

Moreover, when Karthus plays with Lissandra on the same team, he often takes a little more damage than when he plays alone. Receiving more damage may indicate that Lissandra does a poor job of covering Karthus during teamfights.

Synergies between Karthus and Lissandra

Damage Types Compared

Karthus
Lissandra
Physical Damage
Magic Damage
True Damage

Champion Playstyles Contrasted

Karthus
Lissandra

Is Karthus better when played alongside Lissandra?

There is no universally accepted best companion for Karthus that will always be his top synergy. However, Lissandra is a very bad teammate for Karthus. By being on the same team as Karthus, she drops their win rate by -4.7% to 42.6%. This proves that there is a terrible bond between Karthus and Lissandra that results in them performing worse together than without each other.

Lissandra has a lower difficulty than Karthus. That means Karthus players don't need to be careful when enlisting Lissandra allies to play with, as they will need a relatively low level of skill to be able to cooperate well with you.

When playing on the same side, Karthus players should expect to observe an overall large increase in your team’s capacity to deal magic damage. Together, these two can blast through enemies with magic damage.

In contrast, by pairing Karthus and Lissandra together, you may not be granting your side very much sustained damage output. Plan to pick other champs on your team that neutralizes this relative hole in their capabilities.

Regardless of the ability of your Lissandra teammate, you should focus on increasing your income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you should do well, regardless.

Additional Information for Karthus Players

How We Calculated Our Karthus Lissandra Synergy Build and Stats

For this guide on pairing Karthus and Lissandra, we analyzed 408 ranked and recent League of Legends matches. We perform advanced data cleaning and statistical methods to guarantee that our team synergy stats are accurate and reliable. You can be confident that our recommended build to pair Karthus with Lissandra comes from actual data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view your division's most relevant stats and build.

Other Useful Resources

Further Insights to Win with this Champion Pairing

If you would like to learn all of the intricacies of Karthus in order to work well with Lissandra during both the laning and mid / late game phases of LoL matches, you should continue reading to learn a few extra tips and tricks for this champion pairing. If you pay attention to the build and suggestions shown above, you should increase your win rate significantly.

The ideal finished items to have in your Karthus and Lissandra synergy build include Rabadon's Deathcap, Malignance, and Liandry's Torment. When Karthus incorporated at least these three items in his build, he did much better when paired up with Lissandra than with many other typical builds. In fact, Karthus had an average win rate of 42.6% when synergizing his build and playstyle to Lissandra with this build.

To have the highest probability of vanquishing your oponents, you should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the rune sets players chose for Karthus and Lissandra pairings, this combination of runes resulted in the top win rate. Notably, these runes gave a 42.6% win rate overall.

By default, tips, stats, and builds on how to synergize Lissandra with Karthus are given for all skill levels combined. If you would like to narrow the stats and builds to a distinct division, you can use the selection menu earlier in the counter matchup guide.