Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Stay spread out to minimize the impact of Lee Sin's ultimate, Dragon's Rage.
Lee Sin relies heavily on following up with his abilities. Use disables to prevent him from chaining together his abilities and attacks.
Lee Sin has powerful tools to combat physical damage in Iron Will and Cripple but he is still vulnerable to magic damage.
The stat comparisons shown here underscore several vital Karthus versus Lee Sin counter stats that can help us interpret the distinctions between the pair. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Lee Sin’s ratio of NaN, showing that Karthus may be more central to his team's team fighting capability than Lee Sin..
Karthus normally has a similar longest killing spree as his foe does. Commonly, he takes less damage than Lee Sin. This often reflects differing health capacities, but it can also show that the champ with more HP has less mobility and thus is not able to flee from further harm when engaged or poked.
Both League champs are great champions. Both have their pros and cons. In League's current meta, Karthus usually wins when playing against Lee Sin, with a 53.8% win rate. As a result, Karthus makes a great counter for Lee Sin.
While Karthus does have a higher win rate than Lee Sin, when on opposite teams, Karthus also has a greater difficulty level that makes him a more time consuming champion to develop with. You don't need to be too worried when picking Karthus into Lee Sinas his relative depth means you may not be able to reach his full potential without a lot of practice beforehand.
Additionally, Karthus also has some amount of utility and CC, a similar amount to Lee Sin. This often makes her just as valuable during teamfights, especially when facing champions with a ton of burst damage.
While there is not one best champion overall in League of Legends, in Karthus vs Lee Sin matchups, Karthus is the better champ with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your allies during late stage team fights.
Karthus is a great counter to Lee Sin. Make sure you focus your actions on maximizing your gold income and clearing objectives. If you do that, you should hold your own as Karthus against Lee Sin.
If you would like to truly master Karthus in order to counter Lee Sin during both the early game and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this matchup. If you mind the build and tips displayed here, you will grow your win rate by a lot and be closer to League of Legends pro players.
Karthus often accumulates more CS compared to Lee Sin. Champions who typically don't take many minion kills typically don't require much CS to be effective, such as support champions. They are able to scale well off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, usually have to have a lot of items to be effective. In either situation, try to do better than the numbers reported on this page to do well.
The ideal items to have in your Karthus versus Lee Sin build consist of Liandry's Anguish, Morellonomicon, and Shadowflame. When Karthus included at least these three items in his build, he did significantly better versus Lee Sin than with many other typical item sets. In fact, Karthus had an average winrate of 53.8% when playing against Lee Sin with this counter build.
To have the highest chance of beating Lee Sin as Karthus, you should use the Dark Harvest, Taste of Blood, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the runes players chose for Karthus vs Lee Sin battles, this mix of runes yielded the greatest win rate. In fact, these runes provided a 53.8% win rate overall.
By default, tips, stats, and builds on how to beat Lee Sin as Karthus are given for every ranked division. To filter the stats and builds to a distinct rank, you can use the selection menu located earlier on the page.