Karthus vs Zilean Counter Build

How to Beat Zilean as Karthus


We at MOBA Champion summarize millions of recently ranked League rounds each week. Within our database, Karthus engaged Zilean in 1,685 rounds. Having so many games with Karthus vs Zilean provides us a lot of confidence in our capacity to prepare actionable stats and a solid build to shatter your opponent.

This particular champ pairing is somewhat rare. Karthus has to counter Zilean in only 1.4% of his rounds. Unfortunitally, Karthus does a poor job of beating Zilean. On average, Karthus wins a lowly 48.0% of the time the champions fight each other in. In Karthus versus Zilean games, Karthus’s side is 0.0% more likely to earn first blood. This implies that he most likely will be able to get first blood against Zilean.

Matchups Analyzed


Win Rate


Team First Blood


Best Karthus Items to Counter Zilean

The most important items to use in your Karthus versus Zilean build include Rabadon's Deathcap, Void Staff, and Liandry's Anguish. When Karthus combined at least these three items in his build, he did much better vs Zilean than with most other commonly used builds.

Rabadon's Deathcap Item Void Staff Item Liandry's Anguish Item

Best Karthus Runes to Counter Zilean

To have the best probability of beating Zilean as Karthus, you should use the Dark Harvest, Cheap Shot, Eyeball Collection, Ravenous Hunter, Presence of Mind, and Last Stand runes. Of all the runes players chose for Karthus vs Zilean fights, this mixture of runes yielded the highest win rate. We have also included the best Zilean runes to fend off Karthus to help you infer how he will probably be setup against you.

Best Karthus Runes

Dark Harvest Rune Dark Harvest
Cheap Shot Rune Cheap Shot
Eyeball Collection Rune Eyeball Collection
Ravenous Hunter Rune Ravenous Hunter
Presence of Mind Rune Presence of Mind
Last Stand Rune Last Stand

Best Zilean Runes

Arcane Comet Rune Arcane Comet
Manaflow Band Rune Manaflow Band
Transcendence Rune Transcendence
Scorch Rune Scorch
Biscuit Delivery Rune Biscuit Delivery
Cosmic Insight Rune Cosmic Insight


The subsequent tables show some valuable Karthus against Zilean matchup stats that may help you figure out the differences and similarities between the pair. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of 2.2 is worse than Zilean’s ratio of 2.8, indicating that Karthus may be less central to his team's team fighting capability than Zilean. This observation is in large part caused by the difference in kills .

Battle Stats


Karthus Stats
7 3.2
Zilean Stats


Karthus Stats
7.2 5.5
Zilean Stats


Karthus Stats
8.9 12.4
Zilean Stats

Largest Killing Spree

Karthus Stats
2.7 1.4
Zilean Stats

Damage Dealt

Karthus Stats
27488 12926
Zilean Stats

Damage Taken

Karthus Stats
25298 17812
Zilean Stats

Objective Stats

Towers Destroyed

Karthus Stats
5.2 5.6
Zilean Stats

Inhibitors Destroyed

Karthus Stats
0.9 1
Zilean Stats

Dragons Killed

Karthus Stats
2 2.1
Zilean Stats

Barons Killed

Karthus Stats
0.4 0.4
Zilean Stats

Gold Earned

Karthus Stats
11737 8974
Zilean Stats

Minions Killed

Karthus Stats
87 61
Zilean Stats

Karthus typically has a much larger longest kill spree than his foe does. Typically, Karthus takes more damage than Zilean. This typically indicates different amounts of tankyness, but it can also indicate that the champion with more HP has less mobility and thus is unable to escape additional damage when engaged or poked.

Karthus typically totals a bit more CS than Zilean. Champs that do not finish with many minion kills usually do not need much CS to be effective. They are able to scale easily off their abilities alone. Yet, champs with tons of CS, such as carries, usually need a lot of items to be useful. In either case, work to pass the values presented here to do well.

By default, Karthus vs Zilean tips, stats, and build guide are shown for all skill levels combined. To scope the statistics and builds to a specific skill level, you can use the selection menu earlier on the page.

How We Analyze Our Matchups

For this counter guide, we analyzed 1685 Karthus vs Zilean matchups from recent LoL games. We use rigorous data cleaning and processing methods to ensure that our counter stats are of the highest quality. You can rest assured that the recommended build to counter Zilean as Karthus comes from real data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view the most relevant stats and items to your rank.