Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The stats shown here feature some critical Vayne vs. Zeri matchup statistics that can help you understand the differences between the pair. For instance, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is better than Zeri’s KDA ratio of NaN, indicating that Vayne may be more central to her team's team fighting capacity than Zeri..
Vayne typically has a similar longest kill spree as her enemy does. Commonly, she receives a similar amount of damage to Zeri. This often reflects different amounts of tankyness, but it can also indicate that the one champ has less mobility and thus is unable to escape additional damage when poked or engaged.
Both LoL champs are great. Both have their strengths, weaknesses, and counters. In the game's current meta, Vayne usually wins when trying to fight Zeri, with a 55.0% win rate. Therefore, Vayne makes a great counter to Zeri.
While Vayne does have a much higher win rate than Zeri, when they face off with one another, Vayne also has a greater difficulty level that makes her a more challenging champion to pick up and master. You don't need to be too worried when picking Vayne into Zerias her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Additionally, Vayne has some amount of CC and other utility, a similar amount to Zeri. This often makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Vayne vs Zeri matchups, Vayne is the better champion with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your team members during teamfights.
Vayne is a great counter for Zeri. Focus your strategy on keeping up your CS and clearing objectives. If you are able to do that, you should do very well as Vayne against Zeri.
If you would like to learn all of the intricacies of Vayne in order to counter Zeri during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra lessons on this matchup. If you mind the build and tips displayed above, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Vayne typically gets a similar amount of CS compared to Zeri. Champs who typically don't earn much CS often don't require much CS to be valuable teammates, such as sup champs. They are able to scale properly off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, usually require several high cost items to be effective. In either situation, try to exceed the values reported here to do well.
The ideal items to prioritize in your Vayne versus Zeri build include Guinsoo's Rageblade, Wit's End, and Blade of The Ruined King. When Vayne used at least these three pieces in her build, she did significantly better countering Zeri than with most other commonly used item sets. In fact, Vayne had an average win rate of 55.0% when countering Zeri with these items in her kit.
To have the greatest chance of crushing Zeri as Vayne, you should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Taste of Blood, and Treasure Hunter runes from the Precision and Domination rune sets. Of all the rune combinations players picked for Vayne vs Zeri counter picks, this mixture of runes resulted in the highest win rate. Moreover, these runes gave a 55.0% win rate overall.
By default, tips, statistics, and builds on how to beat Zeri as Vayne are presented for all ranked divisions. If you want to scope the statistics and builds to an individual division, you should use the selection menu located earlier in the counter matchup guide.