Vayne Build Guide

LoL Vayne Build Guide

The Best Vayne Runes, Items, and Advice to Dominate Your Competition

217,029 Vayne Builds Analyzed

Best Items for Your Vayne Build

The best items to use in your Vayne build are: Immortal Shieldbow, Infinity Edge, Bloodthirster, and Rapid Firecannon. Additionally, like our rune suggestions, you can also get quality, dedicated, Vayne item builds below for the specific enemy team comp you are playing in your ongoing match. Those who included these pieces in their builds had a better win rate than those who used other builds for Vayne.

Vayne Items to Defeat Focused Team Comps

Best Vayne Runes for Your Next Build

Lethal Tempo Build Rune for Vayne Lethal Tempo
Triumph Build Rune for Vayne Triumph
Legend: Alacrity Build Rune for Vayne Legend: Alacrity
Coup de Grace Build Rune for Vayne Coup de Grace
Gathering Storm Build Rune for Vayne Gathering Storm
Celerity Build Rune for Vayne Celerity
If you are fighting a well-mixed enemy team comp, you should really consider grabbing her the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Gathering Storm, and Celerity runes. In recent games, she won the largest fraction of her games when using these runes. However, if you are fighting a more single focused enemy team comp, such as an AP heavy or a crowd control heavy team, you should instead scrollbrowse a little below to use the best Vayne runes to defeat your particular combination of foes.

Vayne Runes to Beat Dedicated Enemy Teams

Hail of Blades Rune to Fight a Specific Team Comp with a Good Vayne Build Hail of Blades
Taste of Blood Rune to Fight a Specific Team Comp with a Good Vayne Build Taste of Blood
Eyeball Collection Rune to Fight a Specific Team Comp with a Good Vayne Build Eyeball Collection
Ravenous Hunter Rune to Fight a Specific Team Comp with a Good Vayne Build Ravenous Hunter
Triumph Rune to Fight a Specific Team Comp with a Good Vayne Build Triumph
Coup de Grace Rune to Fight a Specific Team Comp with a Good Vayne Build Coup de Grace

Guide to Playing with Vayne

  • Target Condemn such that the enemy champion is pinned against a wall. Use this during teamfights to focus down an enemy.
  • Vayne is very squishy; it's important to be cautious early on and farm up items as fast as possible to help the team later.
  • Vayne's true damage absolutely shreds enemy tanks. In the late game, she's can take just about any champ down, quickly.
  • Practice your positioning. Try to keep your enemy between yourself and a wall to ensure that Condemn can stun them. Doing so can prevent the enemy from being able to engage you.

Summary

We set our Vayne build suggestions by examining 217,029 recently ranked League of Legends rounds with her in them. We only propose the highest winrate Vayne builds that were built by ranked League players enough times for us to propose them. With so many games in our data, we are quite confident in our suggested builds.

Additionally, to view the best Vayne build designed for a different skill rank, you can choose a different skill tier from the dropdown above. The calculated Vayne builds will update to capture that division’s meta.