The Best Runes, Items, and Advice to Dominate Your Competition
We established our Vayne build recommendations by analyzing 200,734 recently ranked League games with her in them. We only propose the highest winrate Vayne builds that were built by ranked gamers enough times for us to suggest them. With so many matches in our data, we are quite confident in our suggested builds.
For more champion specific build tips and tactics, you should check out our tips at the bottom of the page. Additionally, to see Vayne builds tailored to a unique division, choose your desired division from the dropdown menu found above. If you select a different division, the proposed Vayne build will capture that division's meta gameplay.
Best Vayne Runes
If you are trying to beat a well-mixed enemy team composition, you should strongly consider getting Vayne the Press the Attack, Overheal, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes. In recent matches, she won the greatest fraction of her rounds when built with these runes. However, if you are fighting a different enemy team comp, such as an AP heavy or a crowd control heavy team, you should instead look below to find the best Vayne runes to win your particular game.
Versus Selected Team Comp
Best Items for Your Vayne Build
The most important items to use in your Vayne build are: Immortal Shieldbow, Phantom Dancer, Stormrazor, and Guinsoo's Rageblade. Yet, like our rune builds, you can also get quality, dedicated, Vayne item builds further down for the particular enemy team composition you are battling in your ongoing game. Those who included these items in their setups had a greater winrate than those who used other builds for Vayne.
vs AD Heavy Teams
vs AP Heavy Teams
vs CC Heavy Teams
vs Tanky Teams
Guide to Playing with Vayne
- Target Condemn such that the enemy champion is pinned against a wall. Use this during teamfights to focus down an enemy.
- Vayne is very squishy; it's important to be cautious early on and farm up items as fast as possible to help the team later.