Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Miss Fortune is easy to kill if you can reach her; target her first in team fights.
Miss Fortune's speed boost is removed if she is damaged by an enemy.
The stats shown here highlight some significant Vayne against Miss Fortune matchup stats that may help us figure out the differences between the two. As an example, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Miss Fortune’s ratio of NaN, highlighting that Vayne may be more central to her team's team fighting capability than Miss Fortune..
Vayne typically has a similar longest killing spree as her counter does. Typically, she takes a similar amount of damage to Miss Fortune. This is usually reflective of different amounts of tankyness, yet it can also show that the one champion has less mobility and thus is not able to flee from further harm when engaged or poked.
Both League of Legends champions are great. Both champs have their strengths, weaknesses, and counters. In League's current meta, Vayne usually loses when taking on Miss Fortune, with a 48.0% win rate. Therefore, Vayne makes a bad counter for Miss Fortune.
While Vayne does have a lower win rate compared to Miss Fortune, when they face off with one another, Vayne also has a much greater level of difficulty that makes her a more complex champion to pick up and master. You may get destroyed when picking Vayne into Miss Fortuneas her relative depth means that you may not be able to reach her full potential without a lot of practice beforehand.
Furthermore, Vayne has some amount of CC and other utility, a similar amount to Miss Fortune. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't a single best champion in League of Legends, in Vayne vs Miss Fortune matchups, Miss Fortune is the better champion with a lower win rate, more champion depth, and a similar amount of utility to help out your teammates during late stage team fights.
Vayne is a bad counter for Miss Fortune. Make sure you focus your play on keeping up your gold and cs and clearing objectives. If you do that, you should be able to stand on your own as Vayne against Miss Fortune.
To truly master Vayne in order to counter Miss Fortune during both the laning and mid / late game phases of League of Legends, you should keep reading to gather a few extra tips and tricks for this matchup. If you pay attention to the build and stats presented above, you will grow your win rate by a lot and be closer to League of Legends pro players.
Vayne often gets a similar amount of CS compared to Miss Fortune. Champs who on average don't earn much CS typically don't have to have much CS to be effective, such as supports. They are able to scale well off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, typically have to have a lot of items to be effective. In either case, try to do better than the values reported here to do well.
The most crucial items to focus on in your Vayne versus Miss Fortune build include Trinity Force, Statikk Shiv, and Kraken Slayer. When Vayne incorporated at least these three items in her build, she performed a lot better vs Miss Fortune than with most other typical counter builds. In fact, Vayne had an average winrate of 48.0% when playing against Miss Fortune with these items in her kit.
To have the highest chance of coming out on top against Miss Fortune as Vayne, you should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Bone Plating, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the runes players used for Vayne vs Miss Fortune clashes, this composite of runes yielded the greatest win rate. Notably, these runes averaged a 48.0% winrate overall.
If you want to see Vayne vs Miss Fortune tips and counter stats for a a specific player tier, feel free to choose one from the selection menu shown above. By default, the stats and guides displayed are computed using every match completed with both champs.