Cassiopeia with Vayne
How to Synergize Cassiopeia and Vayne
based on 1,809 Cassiopeia with Vayne pairsHow We Analyze Champion Pairings in LoL
Cassiopeia Vayne Synergy Summary
Best Cassiopeia vs Vayne Counter Build
Items
Starter Items
Early Items
Core Cassiopeia Items
Optional Items
Summoner Spells
Skill Order
Runes
Guide to Synergizing Cassiopeia and Vayne
Tips for Playing as Cassiopeia with Vayne
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Advice to Understand How Vayne Will Play
Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Cassiopeia Vayne Synergy Stats
How to Play with Vayne as Cassiopeia in LoL
The Cassiopeia Vayne synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Vayne, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Cassiopeia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA fell from NaN to NaN. This decrease shows that Vayne helps Cassiopeia perform not as well in ranked LoL rounds. Yet, the small difference proves that this performance change is not very impactful.
When Cassiopeia is an ally to Vayne, she gets a small increase in her full damage output. This change could indicate that Vayne helps provide protection for her to dish out more damage or that her presence also helps extend the round's duration. Similarly, when Cassiopeia is played together with Vayne on the same team, he usually scores many fewer killing sprees than when she plays without Vayne. This is contrasting evidence that she is worse when playing synergisticly with Vayne.
Moreover, when Cassiopeia plays with Vayne on the same side, she often takes a little less damage than when she fights alone. Getting dealt not as much damage may mean that Vayne does a decent job of protecting Cassiopeia during team fights.
Synergies between Cassiopeia and Vayne
Damage Types Compared
Champion Playstyles Contrasted
Is Cassiopeia better when played alongside Vayne?
There is no one best ally for Cassiopeia that will 100% of the time be her best teammate. However, Vayne is a pretty good companion for Cassiopeia. By locking into the same side as Cassiopeia, she increases their win rate by 1.0% to 51.3%. This demonstrates that there is pretty good strategic relationship between Cassiopeia and Vayne that results in them performing stronger together than without each other.
Vayne has a lower difficulty than Cassiopeia. That means Cassiopeia players don't need to be careful when lining up Vayne teammates to fight alongside, as they will need a relatively low level of skill to be able to play well with you.
Playing alongside, you will likely witness an overall large increase in your team’s ability to dish out massive AD. Combined, these champions can tear through the other team with a lot of physcial damage.
Conversely, by grouping Cassiopeia and Vayne together, you probably will not be giving your other allies a lot of protection for burst damage. Plan to have other champions on your team that fills this relative disparity in this pairing's kit.
Regardless of the skill of your Vayne ally, you need to focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you will do well anyway.
Other Champion Matchups Against Cassiopeia
Other Top Synergies by Role
Additional Information for Cassiopeia Players
How We Calculated Our Cassiopeia Vayne Synergy Build and Stats
Other Useful Resources
Further Insights to Win with this Champion Pairing
If you would like to truly master Cassiopeia in order to pair well with Vayne during both the lane and mid / late game phases of League matches, you should continue reading to gather some more tricks and insights into this champion pairing. If you use the build and stats shown here, you will increase your win rate significantly.
The top finished items to focus on in your Cassiopeia and Vayne synergy build include Seraph's Embrace, Rylai's Crystal Scepter, and Zhonya's Hourglass. When Cassiopeia combined at least these three pieces in her build, she did much better when paired up with Vayne than with many other common builds. In fact, Cassiopeia had an average winrate of 51.3% helping carry Vayne with this build.
To have the highest probability of annihilating your oponents, Cassiopeia players should equip the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the runes players picked for Cassiopeia and Vayne pairings, this combination of runes resulted in the greatest win rate. Notably, these runes gave a 51.3% winrate overall.
By default, tips, statistics, and builds on how to synergize Vayne with Cassiopeia are displayed for all ranked divisions combined. If you would like to filter the stats and builds to a distinct player tier, you can use the selection menu above.