Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stats shown here highlight some critical Annie versus Karthus matchup statistics that may help you distinguish the differences and similarities between these two champions. For instance, Annie’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karthus’s KDA ratio of NaN, showing that Annie may be more central to her team's team fighting effectiveness than Karthus..
Annie often has a slightly smaller longest kill spree than her enemy does. Typically, she receives less damage than Karthus. This typically indicates differing health capacities, yet it can also imply that the one champ has less agility and thus is not able to flee from further damage when poked or engaged.
Both League of Legends champions are great. Both have their strengths, weaknesses, and counters. In the game's current meta, Annie usually wins when trying to fight Karthus, with a 54.6% win rate. Therefore, Annie makes a great counter for Karthus.
While Annie does have a much higher winrate compared to Karthus, when they face off with one another, Annie also has a lower level of difficulty that makes her a less complex character to learn and master. You should be be fine when picking Annie into Karthus.
Furthermore, Annie also has a good amount of CC and other utility, a similar amount to Karthus. This often makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there isn't a single best champion overall in League of Legends, in Annie vs Karthus matchups, Annie is the better champion with a noticably higher win rate, less champion complexity, and a similar amount of utility to help out your allied champions during team fights.
Annie is a great counter to Karthus. You will do well by focussing your actions on increasing your gold income and clearing objectives. If you are able to do that, you should do very well as Annie against Karthus.
To truly master Annie to counter Karthus during both the early game and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tricks and insights into this matchup. If you mind the build and suggestions displayed here, you will grow your win rate by a lot and be closer to League of Legends pro players.
Annie often accumulates a similar amount of CS compared to Karthus. Champs who typically don't take many minion kills often don't have to have much CS to be effective, such as sup champs. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically require a lot of items to be effective. In either case, try to surpass the numbers displayed here to do well.
The best items to prioritize in your Annie versus Karthus build include Luden's Tempest, Zhonya's Hourglass, and Shadowflame. When Annie bought at least these three items in her build, she performed much better when facing Karthus than with many other common builds. In fact, Annie boasted an average winrate of 54.6% when playing against Karthus with these items in her kit.
To have the highest chance of crushing Karthus as Annie, you should equip the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Manaflow Band, and Absolute Focus runes from the Domination and Sorcery rune sets. Out of all the rune combinations we have analyed for Annie vs Karthus counters, this sequence of runes yielded the greatest win rate. Notably, these runes provided a 54.6% winrate overall.
By default, tips, stats, and builds on how to beat Karthus as Annie are displayed for every ranked division. If you would like to scope the stats and builds to a specific skill level, you should use the selection menu at the top of this page.