Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Kai'Sa is very vulnerable to getting outranged by mages and long range carries.
Make sure to place wards in your blind spots so you can see Kai'Sa coming.
Kai'Sa is very good at picking off isolated enemies. Stick together against her.
The stat comparisons shown here underscore some valuable Cassiopeia vs. Kai'Sa matchup stats that may help you figure out the differences between the pair. Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Kai'Sa’s ratio of NaN, indicating that Cassiopeia may be more central to her team's team fighting capability than Kai'Sa..
Cassiopeia usually has a similar longest kill spree as her matchup does. Commonly, she receives more damage than Kai'Sa. This typically indicates differing health capacities, but it can also imply that the champ with increased health has less agility and thus is unable to escape further harm when engaged or poked.
Both LoL champions are great. Both have their pros and cons. In the game's current meta, Cassiopeia usually wins when taking on Kai'Sa, with a 53.5% win rate. As a result, Cassiopeia makes a great counter for Kai'Sa.
While Cassiopeia does have a higher winrate than Kai'Sa, when they face off with one another, Cassiopeia also has a much greater difficulty level that makes her a more challenging champ to learn. You should be be fine when picking Cassiopeia into Kai'Saas her relative depth means that you may not be able to unleash her full potential without a lot of practice beforehand.
Furthermore, Cassiopeia has a good amount of CC and other utility, a similar amount to Kai'Sa. This makes her just as valuable during team fights, especially when facing champions with a lot of burst damage.
While there is not a single best champion for every situation in League of Legends, in Cassiopeia vs Kai'Sa matchups, Cassiopeia is the better champion with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your teammates during teamfights.
Cassiopeia is a great counter to Kai'Sa. Focus your play on increasing your gold and cs and destroying objectives. If you are able to do that, you should hold your own as Cassiopeia against Kai'Sa.
If you would like to truly master Cassiopeia to counter Kai'Sa during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and tips shown above, you should increase your win rate significantly and be that much closer to League of Legends pro players.
Cassiopeia most often gets a similar amount of CS compared to Kai'Sa. Champions who typically don't get much CS usualy don't require much CS to be valuable teammates, such as supports. These kinds of champions are capable of scaling well off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, often need a lot of items to be effective. In either case, try to do better than the values displayed on this page to do well.
The top items to prioritize in your Cassiopeia versus Kai'Sa build include Liandry's Anguish, Seraph's Embrace, and Void Staff. When Cassiopeia used at least these three items in her build, she did much better against Kai'Sa than with most other common builds. In fact, Cassiopeia boasted an average win rate of 53.5% when countering Kai'Sa with this build.
To have the greatest chance of coming out on top against Kai'Sa as Cassiopeia, you should take the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Out of all the rune combinations players picked for Cassiopeia vs Kai'Sa matchups, this set of runes yielded the best win rate. Moreover, these runes gave a 53.5% win rate overall.
By default, tips, stats, and builds on how to beat Kai'Sa as Cassiopeia are given for all ranked divisions combined. If you would like to scope the statistics and builds to a particular division, you may use the selection menu at the top of this page.