Karthus vs Vayne Counter Build

How to Beat Vayne as Karthus

Summary

We get our matchup stats from the millions of recently ranked League of Legends games that we evaluate each week. This Karthus versus Vayne matchup review resulted from an analysis of 8,957 ranked matches where both champions clashed against each other.

This pairing is somewhat uncommon. Karthus has to counter Vayne in only 7.3% of his games. Unfortunitally, Karthus does a pathetic job of beating Vayne. On average, Karthus wins a lowly 46.0% of games the champs battle one another in. In Karthus versus Vayne rounds, Karthus’s team is 5.0% less probable to obtain first blood, indicating that he probably won't be able to get first blood against Vayne.

Matchups Analyzed

8,957

Win Rate

46%

Team First Blood

45%

Best Karthus Items to Counter Vayne

The most important items to have in your Karthus versus Vayne build consist of Rabadon's Deathcap, Void Staff, and Night Harvester. When Karthus bought at least these three pieces in his build, he performed significantly better when fighting Vayne than with most other common builds.

Rabadon's Deathcap Item Void Staff Item Night Harvester Item

Best Karthus Runes to Counter Vayne

To have the best probability of beating Vayne as Karthus, Karthus players should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ravenous Hunter, Coup de Grace, and Presence of Mind runes. Out of all the rune sets players chose for Karthus vs Vayne counterpicks, this mix of runes resulted in the highest win rate. We have also shown the top Vayne runes to counterpick against Karthus in order to help you grasp how she will likely be played against your champion.

Best Karthus Runes

Dark Harvest Rune Dark Harvest
Cheap Shot Rune Cheap Shot
Eyeball Collection Rune Eyeball Collection
Ravenous Hunter Rune Ravenous Hunter
Coup de Grace Rune Coup de Grace
Presence of Mind Rune Presence of Mind

Best Vayne Runes

Press the Attack Rune Press the Attack
Triumph Rune Triumph
Legend: Alacrity Rune Legend: Alacrity
Coup de Grace Rune Coup de Grace
Ravenous Hunter Rune Ravenous Hunter
Taste of Blood Rune Taste of Blood

Stats

The following tables show several strategic Karthus vs. Vayne matchup statistics that can help you understand the distinctions between this pair of champions. As an example, Karthus’s KDA ratio ([kills + assists] / deaths) of 2.3 is similar to Vayne’s ratio of 2.1, highlighting that Karthus may be just as central to his team's team fighting effectiveness than Vayne.

Battle Stats

Kills

Karthus Stats
7.5 8.5
Vayne Stats

Deaths

Karthus Stats
7.3 6.9
Vayne Stats

Assists

Karthus Stats
9.3 5.7
Vayne Stats

Largest Killing Spree

Karthus Stats
2.8 3.5
Vayne Stats

Damage Dealt

Karthus Stats
27080 19019
Vayne Stats

Damage Taken

Karthus Stats
24391 22362
Vayne Stats

Objective Stats

Towers Destroyed

Karthus Stats
5.1 5.6
Vayne Stats

Inhibitors Destroyed

Karthus Stats
0.9 1
Vayne Stats

Dragons Killed

Karthus Stats
1.9 2.1
Vayne Stats

Barons Killed

Karthus Stats
0.4 0.5
Vayne Stats

Gold Earned

Karthus Stats
11783 12200
Vayne Stats

Minions Killed

Karthus Stats
87 151
Vayne Stats

Karthus often has a slightly smaller longest killing spree than his opponent does. On average, Karthus receives a similar amount of damage to Vayne. This commonly reflects different amounts of tankyness; however, it can also illustrate that the one champ has less agility and thus is unable to escape additional harm when poked or engaged.

In Karthus vs Vayne matchups, Karthus commonly gets much less CS than Vayne. Champions who on average do not acquire a lot of minion kills typically don't need much CS to be useful. Instead, they are able to scale well off of their abilities alone. However, champions with plenty of minion kills, such as hyper-carries, usually need a lot of items to be effective. In either case, work to best the averages displayed here to do well.

If you want to get Karthus vs Vayne tips and builds for a a distinct division, please select one from the selection menu menu above. By default, the stats and strategies displayed are computed using all matches played with these champions.

How We Analyze Our Matchups

For this counter guide, we analyzed 8957 Karthus vs Vayne matchups from recent LoL games. We use rigorous data cleaning and processing methods to ensure that our counter stats are of the highest quality. You can rest assured that the recommended build to counter Vayne as Karthus comes from real data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view the most relevant stats and items to your rank.