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How to Synergize Karthus with Vex on the Same TeamKarthus is in the b tier of champions

Karthus with Vex

How to Win With Karthus and Vex Paired TogetherKarthus is in the b tier of champions
Mage
Mage

How to Synergize Karthus and Vex

based on 674 Karthus with Vex pairs
Win Rate
45.4 %
K/D/A
2.21
Pick Rate
1.4 %

How We Analyze Champion Pairings in LoL

We download the results of from millions of LoL games straight from Riot Games each week. Karthus has gone into battle with Vex in 674 recently played, competitive games. By gathering so much accurate data directly from the creators of LoL, we are sure that we can give you high-quality, accurate builds to help Karthus play with Vex. It is very rare for Karthus to play with Vex on the same team. This has only taken place in approx. 1.4% of rounds with Karthus.

Karthus Vex Synergy Summary

Unfortunately, Karthus does a awful job of teaming up with Vex. Usually, he wins a dismal 45.4% of rounds the champions try and work together in. If you want to do better as Karthus when fighting on the same team as Vex by figuring out how to better synergize your gameplay with them, then dig into the full build (with items, runes, summoner spells, and skills) below!

Best Karthus vs Vex Counter Build

Items

Starter Items

Time Target
Scorchclaw PupHealth Potion

Early Items

~5 Mins
Amplifying TomeGlowing Mote

Core Karthus Items

~22 Mins
Rabadon's DeathcapMalignanceShadowflame

Optional Items

StormsurgeLiandry's TormentLuden's CompanionVoid Staff

Summoner Spells

summonerexhaust summoner spell D
summonersmite summoner spell F

Skill Order

First skill for Karthus to level upq
>
Second ability for Karthus to level upe
>
Last skill for Karthus to max outw

Runes

InspirationFirst StrikeMagical FootwearFuture's MarketCosmic Insight
DominationEyeball CollectionUltimate Hunter
Adaptive ForceAdaptive ForceArmor
Karthus's passive ability p
Karthus's q ability q
Karthus's w ability w
Karthus's e ability e
Karthus's ultimate ability r
1
Q
2
E
3
Q
4
W
5
Q
6
R
7
Q
8
E
9
Q
10
E
11
R
12
E
13
E
14
W
15
W
16
R

Guide to Synergizing Karthus and Vex

Tips for Playing as Karthus with Vex

Lay Waste is very strong at farming minions and harassing enemy champions.

Ask your allies to help point out when you should use Requiem to get kills in different lanes.

Karthus Vex Synergy Stats

Karthus Image
Win Rate
45.4 %
VS
Win Rate
54.6 %
Vex Image
6.8
< Kills >
7
7.5
< Deaths >
7.6
9.8
< Assists >
9.5
1.61
< Killing Sprees >
1.63
72
< Minions Killed >
88
0.99
< Dragons Killed >
0.89
0.27
< Inhibitors >
0.28
250
< Physical Damage >
246
28,351
< Magic Damage >
29,153
2,086
< True Damage >
2,031
30,689
< Damage Dealt >
31,430
30,557
< Damage Taken >
29,785
12,652
< Gold Earned >
12,799
1.03
< Towers >
1.08
0.23
< Baron Takedowns >
0.23
10,283
< Total Healing >
9,279
14,621
< Experience >
14,921
20
< Vision Score >
19
8
< Wards Placed >
7
226
< Time Dealing CC >
221

How to Play with Vex as Karthus in LoL

The Karthus Vex synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vex, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.

Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Vex. His KDA fell from NaN to NaN. This negative change shows that Vex helps Karthus perform worse in ranked LoL rounds. Yet, the small difference shows that this performance change is not very impactful.

When Karthus tries to synergize with Vex, he gets a little decrease in his full damage dealt. This could demonstrate that Vex does not provide cover for him to dish out more damage or that their allyship also helps increase the match's duration. Similarly, when Karthus is played alongside Vex on the same team, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing synergisticly with Vex.

Additionally, when Karthus plays with Vex on the same team, he often takes a little more damage than when he fights alone. Taking more damage could mean that Vex does a poor job of covering Karthus during teamfights.

Synergies between Karthus and Vex

Damage Types Compared

Karthus
Vex
Physical Damage
Magic Damage
True Damage

Champion Playstyles Contrasted

Karthus
Vex

Is Karthus better when played alongside Vex?

There is no top champion pairing for Karthus that will always be his top synergy. Yet, Vex is a below average ally for Karthus. By locking into the same team as Karthus, they decreases their win rate by -1.9% to 45.4%. This demonstrates that there is a harmful bond between Karthus and Vex that results in them performing worse together than alone.

Vex has a much lower diffuclty than Karthus. That means you don't need to be cautious when arranging Vex teammates to play with, as they will have to have a much lower level of skill to play well with you.

Fighting cooperatively, Karthus players should expect to witness an overall large increase in your team’s ability to deal magic damage. Together, these two can blast through enemies with magic damage.

Conversely, by aligning Karthus and Vex together, you will not be giving your side a lot of attack damage. Make sure to include other champs on your team that nullifies this hole in this pairing's abilities.

Regardless of the ability of your Vex ally, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you should do well, regardless.

Additional Information for Karthus Players

How We Calculated Our Karthus Vex Synergy Build and Stats

For this guide on pairing Karthus and Vex, we analyzed 674 ranked and recent League of Legends matches. We perform advanced data cleaning and statistical methods to guarantee that our team synergy stats are accurate and reliable. You can be confident that our recommended build to pair Karthus with Vex comes from actual data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view your division's most relevant stats and build.

Other Useful Resources

Further Insights to Win with this Champion Pairing

If you would like to learn all of the intricacies of Karthus to synergize with Vex during both the early game and mid / late game phases of League of Legends rounds, you should keep reading to pick up a few extra tips and tricks for this champion pairing. If you pay attention to the build and tips presented here, you will increase your win rate significantly.

The most important finished items to get in your Karthus and Vex synergy build consist of Rabadon's Deathcap, Malignance, and Shadowflame. When Karthus incorporated at least these three great items in his build, he did a lot better as an ally of Vex than with most other typical builds. In fact, Karthus boasted an average winrate of 45.4% when synergizing his build and playstyle to Vex with these items in his kit.

To have the greatest probability of vanquishing your oponents, Karthus players should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the runes that we analyzed for this team composition, this mix of runes yielded the greatest win rate. In fact, these runes averaged a 45.4% winrate overall.

By default, tips, stats, and builds on how to synergize Vex with Karthus are shown for all ranked divisions. If you want to narrow the stats and builds to a distinct player tier, you should use the selection menu located earlier in the counter matchup guide.